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P Clayette Selected Research

PMS 601

11/2000PMS-601, a new platelet-activating factor receptor antagonist that inhibits human immunodeficiency virus replication and potentiates zidovudine activity in macrophages.
6/2000[Antiretroviral ant anti-inflammatory properties of a novel platelet activation factor antagonist, PMS-601].
6/2000Structure-activity relationships in platelet-activating factor (PAF). 10. From PAF antagonism to inhibition of HIV-1 replication.

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P Clayette Research Topics

Disease

10HIV Infections (HIV Infection)
05/2008 - 02/2000
4Infections
05/2008 - 06/2000
3Acquired Immunodeficiency Syndrome (AIDS)
11/2008 - 07/2001
2Prion Diseases (Transmissible Spongiform Encephalopathies)
08/2009 - 08/2009
1Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
08/2009
1Bovine Spongiform Encephalopathy (Mad Cow Disease)
08/2009
1Neuroinflammatory Diseases
05/2008
1Murine Acquired Immunodeficiency Syndrome (MAIDS)
02/2008
1Neuroblastoma
10/2007
1Scrapie
10/2007
1Neoplasms (Cancer)
01/2006
1Virus Diseases (Viral Diseases)
01/2006
1Multiple Sclerosis
01/2002
1Cardiovascular Diseases (Cardiovascular Disease)
05/2001
1Inflammation (Inflammations)
05/2001
1Neurodegenerative Diseases (Neurodegenerative Disease)
05/2001
1Necrosis
08/2000
1Dementia (Dementias)
06/2000

Drug/Important Bio-Agent (IBA)

3Glutathione (Reduced Glutathione)IBA
02/2008 - 09/2001
3PMS 601IBA
11/2000 - 06/2000
2PrionsIBA
08/2009 - 08/2009
2Prion ProteinsIBA
08/2009 - 10/2007
2Peptide Hydrolases (Proteases)FDA Link
08/2009 - 06/2000
2Chemokine CCL3IBA
05/2008 - 08/2000
2AntioxidantsIBA
02/2008 - 05/2001
2CytokinesIBA
12/2007 - 08/2000
1DNA (Deoxyribonucleic Acid)IBA
05/2008
1CCR5 Receptors (CCR5 Receptor)IBA
05/2008
1Serotonin (5 Hydroxytryptamine)IBA
05/2008
1Valproic Acid (Depakote)FDA LinkGeneric
10/2007
1Protein Isoforms (Isoforms)IBA
10/2007
1Antiviral Agents (Antivirals)IBA
01/2006
1HLA-DR2 Antigen (HLA DR2 Antigen)IBA
01/2002
1Myelin Basic ProteinIBA
01/2002
1Acetylcysteine (Siran)FDA LinkGeneric
09/2001
1ProdrugsIBA
09/2001
1Free RadicalsIBA
07/2001
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2000
1Interleukin-6 (Interleukin 6)IBA
08/2000
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
06/2000
1Thymidine KinaseIBA
06/2000
1dTMP kinaseIBA
06/2000
1Platelet Activating FactorIBA
06/2000
1Messenger RNA (mRNA)IBA
06/2000
1MS 8209IBA
02/2000
1Amphotericin B (Amphotericin)FDA LinkGeneric
02/2000

Therapy/Procedure

3Highly Active Antiretroviral Therapy (HAART)
11/2008 - 06/2000